alkenyl group- the hydrocarbon group formed when a hydrogen atom is removed from an alkene group. alkoxide- an organic functional group formed when a hydrogen atom is removed from the hydroxyl group of an alcohol when it is reacted with a metal. alkoxy group- functional group containing an al...
1a–c). Specifically, we develop a polymer network comprised of poly(acrylic) acid functionalized with N-hydroxysuccinimide ester (PAA-NHS ester) interpenetrated with and grafted to a hydrophilic polyurethane (PU). A key innovation of this material is the ability to process it into a ...
The binding of intrinsically disordered proteins to globular ones can require the folding of motifs into α-helices. These interactions offer opportunities for therapeutic intervention but their modulation with small molecules is challenging because they
Lactonization occurs between the carboxyl group of the terminal amino acid (Gln) and the hydroxyl group on the side chain of the fourth amino acid (Ser). Its common peptide sequence is Thr-Gly-Ala-Ser-His-Gln-Gln, corresponding to a cationic peptide. Four different FA have been detected ...
The α1(VI) and α2(VI) chains have a similar size and a short collagenous sequence flanked by three type A-like domains, one at the amino end and two at the carboxyl end. The α3(VI) chain is three times larger than the other two chains and most of the additional sequences are...
Building blocks synthesized have various functions and functionality: polyols, polyacids, polyamines and dicyclocarbonates from vegetable oils and from glycerine derivatives. They were used for the synthesis of biobased polyurethanes, polyhydroxyurethanes and epoxy resins....
In an embodiment of the present invention, the pharmaceutical composition is a tablet, capsule, cachet, lozenge, dispensable powder; powder for suspension, or granule, or packet and is comprised of the dry substances in approximate weights and/or activity units as described below in Table Nos. ...
Glutamic peptidases, from the MEROPS family G1, are a distinct group of peptidases characterized by a catalytic dyad consisting of a glutamate and a glutamine residue, optimal activity at acidic pH and insensitivity towards the microbial derived protease inhibitor, pepstatin. Previously, only glutamic...
et al. RNase E polypeptides lacking a carboxyl-terminal half suppress a mukB mutation in Escherichia coli. J. Bacteriol. 178, 3917–3925 (1996). 16. Kohn, H. & Widger, W. The molecular basis for the mode of action of bicyclomycin. Curr. Drug Targets Infect. Disord. 5, 273–295 (...
To quantitatively explore the effect of pH, we examined the behaviour of carboxylated melamine resin (COOH) particles where the charge arises from carboxyl groups characterized by a nominal pK ≈ 4.5. We observed a clear maximum |w| in the range of pK < pH < pK +3 , ...