抗Ro/干燥综合征抗原A(Sjögren's syndrome type A,SSA)抗体和抗La/干燥综合征抗原B(Sjögren's syndrome type B,SSB)抗体都属于抗核抗体谱,常见于系统性红斑狼疮、干燥综合征、未分化结缔组织病及无症状患者,约1%的孕妇抗SSA...
Lehner T, Harty WJ, Doubleday B. (1987). Antibodies to a streptococcal antigen in gingival capillary and crevicular fluid washings, collected from man and non-human primates. Archives of Oral Biology 32, 1 17-1 22.Lehner, T., Harty, W. and Doubleday, B.: Antibodies to a streptococcal...
Onset of candidemia is associated to a significant rise of anti-MP65 and anti-β1,6-glucan antibodies. The graph shows the individual titers of anti-MP65 (Panel a) or anti-β1,6-glucan IgGs (Panel b) measured in control (n = 69) and candidemic patients (n = 71). Sera...
such as those consisting ofantibodies,lymphocytes, or messenger RNA (mRNA), that is administered primarily to preventdisease.A vaccine can conferactive immunityagainst a specific harmful agent by stimulating theimmune systemto a...
Monoclonal antibodies Monoclonal antibodies synthesized to target specific ligands or receptors involved in angiogenesis would be the most straightforward approach to neutralize specific pathogenic pathways. The use of protein-based drugs is technically challenging; however, many monoclonal antibody-based drugs...
our structural analysis related to the various neutralization clusters present on the RBD and the identification of additional putative antibody partner(s) is instructive for the development of an optimized therapeutic cocktail of antibodies for treating COVID-19. Principles of NAb-antigen interactions re...
The PBMCs were tested for plasmid DNA at baseline and 16 weeks. Immune Responses Samples were processed and cryopreserved by published methods.6,7 A 10-day interferon (IFN)-γ enzyme-linked immunosorbent spot assay was used to measure the antigens (6 well-replicates); overlapping peptide pools...
Natural SARS-CoV-2 infection and vaccination against COVID-19 both contribute to building the population’s immunity. Immune responses are multifaceted but single components that are easy to measure such as antibodies are used in epidemiological studies to answer emerging questions such as what is th...
The pivotal phase 3 study, PROTECT, showed that this 3-antigen HBV (3A-HBV) vaccine is highly immunogenic for adults, including older adults and those with well-controlled chronic conditions.15 The 3A-HBV vaccine may provide more opportunities for the immune system to respond with antibodies to...
Anti-SARS-CoV-2 IgM/IgG antibodies detection using a patch sensor containing porous microneedles and a paper-based immunoassay Leilei Bao, Jongho Park, Boyu Qin & Beomjoon Kim Scientific Reports volume 12, Article number: 10693 (2022) Cite this article 12k Accesses 27 Citations 390 Altmetri...