The present invention relates to the production of a compound for treating a quinolone having the 5-HT1A receptor subtype-related central nervous system disorder patients medicament, the medicament comprising as an active ingredient of the formula (1) represents the derivative or a salt thereof: ...
1 Interactions of 5-HT1A receptor agonist or antagonist with diltiazem on pentobarbital-induced LORR. (a) Effects of 8-OH-DPAT, diltiazem and their co-administration on pentobarbital-induced LORR in mice. Mice received diltiazem (2 mg/kg, p.o.) for 90 min and 8-OH-DPAT (0.5 mg/kg, i...
产品描述Gepirone is a 5-HT1A receptor agonist belonging to the buspirone family. Gepirone HCl possesses greater selectivity for the 5-HT1A receptor than SSRIs. 分子量359.47 分子式C19H29N5O2 CAS No.83928-76-1 存储 Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping...
Here we describe the effects of NLX-112, a highly selective and efficacious 5-HT1A receptor agonist, on LID in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated marmosets, a non-human primate model of PD. NLX-112 exhibited modest plasma half-life (~2h) and marked plasma ...
5-HT1A receptor agonist 8-OH-DPAT (0.2 and 0.5聽mg/kg) decreased aggressive behavior in both A infant and adult rats. The desensitization of 5-HT1A ... Vladimir,S.,Naumenko,... - 《Behavioural Brain Research》 被引量: 30发表: 2013年 加载更多来源...
5HT1A Receptor抗体该基因编码一种G蛋白偶联受体,5-羟色胺(血清素),属于5-羟色胺受体亚家族。血清素与许多生理过程和病理条件有关。这种基因在小鼠体内的失活会导致行为与焦虑和应激反应的增加相一致。5HT1A Receptor抗体该基因启动子突变与月经周期依赖性周期性发热有关。[ 2012 ] RefSeq提供的,君。
1. Azapirones, selective partial agonists at the 5-HT1A receptor subtype, induce hypothermia and corticotropin (ACTH)/cortisol release as specific function... Lesch,Klaus-Peter - Progress in neuro-psychopharmacology & biological psychiatry 被引量: 409发表: 1991年 The 5-HT(1A) receptor agonist 8...
5-羟色胺受体1A抗体(5HT1A Receptor) 价格¥980 起批量≥1支 最小起订1支 供货总量50支 发货地址浙江省温州市 建议售价¥980/支 更新日期2024年09月19日 产品规格50ul 洽谈立即询价查看联系方式 收藏产品发送留言QQ交流 VIP2年 温州科淼生物科技有限公司 ...
在中国,截至 2022 年底,全国约有9500 万成年人患有不同程度的抑郁症状,比 2017 年增加了近 20%。这一趋势推动了对高效治疗药物的需求增长,尤其是针对抑郁症的新型治疗手段——5- 羟色胺受体激动剂(5-HT receptor agonists)。 二、市场需求现状 1. 市场规模与增长速度 ...
5-HT1A receptor Agonist Antagonist Depression Active ingredients of traditional Chinese medicine Sorry, something went wrong. Please try again and make sure cookies are enabled References [1] Z.S. Gu, Y. Xiao, Q.W. Zhang, J.Q. Li