[1,4]benzoxazines]Two new series of 1,3-dihydrospiro[2H-indole-ozazine] derivatives were synthesized, the 1,3-dihydrospiro[2H-indole-2,3′-[3H]pyrimido[5,4]pyrimido[5,4-f][1,4]benzoxaines] 4-10 and the 1,3-dihydrospiro[2H-indole2,7′-[7H]thiazolo-[5,4-f][1,4]benzoxaines...
Fructose consumption induces metabolic syndrome to increase cardiovascular disease risk. Cinnamaldehyde and allopurinol possess anti-oxidative and anti-inflammatory activity to relieve heart injury in metabolic syndrome. But the mechanisms of fructose-in
Although a number of genetic defects are commonly associated with acute myeloid leukemia (AML), a large percentage of AML cases are cytogenetically normal. This suggests a functional screen for transforming genes is required to identify genetic mutations that are missed by cytogenetic analyses. We ut...
We studied frequency and mechanism of inactivation of the p16 gene in various types of childhood acute lymphoblastic leukemia (ALL) using 36 leukemic cell lines established from children (B precursor-ALL, 28; B-ALL/Burkitt's lymphoma, 3; and T-ALL, 5). On Southern blot, homozygous deletions...
Intraventricular CARv3-TEAM-E T Cells in Recurrent Glioblastoma 摘要 摘要 在此项由研究者发起,首次应用于人体的开放标签研究中,3例复发性胶质母细胞瘤患者接受了CARv3-TEAM-E T细胞治疗,CARv3-TEAM-E T细胞是经过基因工程改造,靶向表皮...
近期在 Authorea & Research Square 预印论文 (1-4/4) 胡春松博士@南昌大学 1. Review Effects of E(e)SEEDi as a “super-vaccine” on blood, cardiac, vascular health and its macro-mechanisms Here is the permanent link to the preprint on Authorea: ...
The live-cell imaging Incucyte® system was used to track the effects on the cell growth and cell death kinetics of z-VAD-FMK, Fer-1, NAC, and CPX, following MDM4 inhibition. (c) Representative fluorescence microscopy images. (e,f) The SKBr3 (GFP tagged) cell line was treated with...
1, Veera C.S.R. Chittepu 2, Poonam Kalhotra 1, José Proal-Nájera 3, Guillermo Osorio-Revilla 2,*and Tzayhrí Gallardo-Velázquez 1,* 1 Departamento de Biofísica, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional. Prolongación de Carpio y Plan de Ayala S/N. Co...
α4+β7hiCD4+ memory T cells harbor most Th-17 cells and are preferentially infected during acute SIV infection. Alpha4 (+)beta7 (hi)CD4 (+) memory T cells harbor most Th-17 cells and are preferentially infected during acute SIV infection [J]. Mucosal Immunol... Kader,M.,Wang,......
春,带来了芬芳艳丽的花朵,带来了péng勃 a 的草木,带来了对未来的一份憧憬;夏,带来了缤纷绚丽的骄阳,带来了挺bá b的树木,带来了奋斗的脚印;秋,带来了 c 的落叶,带来了温柔的秋雨,带来了丰收的喜讯;冬,带来了 d 的雪花,带来了素雅的天地,带来了睿智的沉思。春来秋去,风光无限,四季的美景是大自然给人呈现...