Alzheimer’s disease (AD) is the most common cause of dementia [1], but the link between pathophysiological processes and the emergence of dementia has not been fully elucidated. Sperling et al. hypothesized that the AD pathology begins many years prior to the onset of dementia, and that amyl...
Neurodegenerative diseases such as Parkinson’s (PD) and Alzheimer’s disease (AD), the prevalence of which is rapidly rising due to an aging world population and westernization of lifestyles, are expected to put a strong socioeconomic burden on health s