Mu-Conotoxin SIIIA 供应商 Alomone 产品货号 ALO-STC-450-50 产品报价 ￥已停产 产品说明书 点击查看 购买方式 银行转账、电汇、支票、现金,在线支付宝及网银支付,或直接与我们电话联系400-6800-868 产品新闻 背景资料 µ-Conotoxin SIIIA is a synthetic peptide purified to homogeneity, originally isolated fr...
Although µ-conotoxin SmIIIA shares several biochemical characteristics with other µ-conotoxins (the arrangement of cysteine residues and a conserved arginine believed to interact with residues near the channel pore), it has distinctive features such as the absence of hydroxyproline. In voltage-...
Neutral substitution of certain toxin charges (KIIIA-H12A and KIIIA-R14A), increases the toxin's selectivity towards hNav1.7. Understanding how drugs can target this unique hNav1.7 site will aid the development of subtype specific blockers against this channel to help ...
Folding similarity of the outer pore region in prokaryotic and eukaryotic sodium channels revealed by docking of conotoxins GIIIA, PIIIA, and KIIIA in a Na... Voltage-gated sodium channels are targets for many Zhorov,Boris,S.,... - 《Journal of General Physiology》 被引量: 33发表: 2014...
SmIIIA is a new micro-conotoxin isolated recently from Conus stercusmuscarum. Although it shares several biochemical characteristics with other micro-conotoxins (the arrangement of cysteine residues and a conserved arginine believed to interact with residues near the channel pore), it has several ...
The invention discloses a genetic engineering preparation method for mu-conotoxin-KIIIA, which comprises: inserting a mu-conotoxin-KIIIA gene into a prokaryotic expression vector with Trx-tag to construct a recombinant prokaryotic expression vector; and transferring Escherichia coli with the recombinant ...