In Cox regression analysis, elevated GGT (> 56 U/L) remained an independent predictor of death both in primary (p = 0.011) and in secondary prevention (p = 0.006). Patients with elevated GGT and renal insufficiency defined by an estimated glomerular filtration rate < 60 ml/min/1.73 m(2)...
In this context, it is plausible that elevated γ-GT in liver disease shares some common mechanisms in dementia. We hypothesized that γ-GT may be independently associated with dementia. Therefore, the aim of this study was to investigate the impact of γ-GT in dementia and the association ...
Background A recently published study suggests that Gamma-Glutamyltransferase (GGT) in midlife is related to an increased risk of dementia. In the present longitudinal study, we explore the effects of serum GGT on cognitive decline and dementia also in more advanced ages. Methods We analyzed GGT ...
GGTP is inducible, and thus levels may be elevated by ingestion of phenytoin or alcohol in the absence of other clinical evidence of liver disease. 4. Because of its long half-life of 26 days, GGTP is limited as a marker of surreptitious alcohol consumption. 5. Its major clinical use is...
aminotransferase (ALT) because if elevated it would indicate alcohol related liver disease [1]. GGT, because of its ubiquitous distribution within the liver, is elevated in all types of liver disease [2]. In the absence of significant liver disease, the myth that a raised GGT is sensitive an...
In patients presenting with heart failure (HF), left ventricular (LV) ejection fraction (EF) will be normal in 50% of cases. Together with elevated natriuretic peptides and structural changes, such as left atrial enlargement, the diagnosis of HF with preserved ejection fraction (HFpEF) can be...
The use of enzyme-inducing antiepileptic drugs (AEDs) can lead to an increase in the serum level of GGT. In liver function tests, GGT level is one of the first to appear elevated.DOI: 10.1080/20014091084227 年份: 2009 收藏 引用 批量引用 报错 分享 ...
Age at diagnosis was positively associated with mortality: the adjusted hazard ratio (HR) was 1.08 (95% CI 1.01–1.15) per 5 years increase; elevated baseline FPG and serum GGT were associated with 1.39- (95% CI: 1.08–1.79) and 1.53- (95% CI: 1.19–1.97) fold mortality, ...
CONCLUSIONS: This study showed that elevated GGT could be a predictor for hypertension in drinkers and the relationship between alcohol consumption and hypertension was shown only among those with GGT 30 U/L at baseline. These findings suggest that increased serum GGT levels may reflect individual ...
et al. Elevated serum levels of alanine aminotransferase and gamma glutamyltransferase are markers of inflammation and oxidative stress independent of the metabolic syndrome. Atherosclerosis 189, 198–205, https://doi.org/10.1016/j.atherosclerosis.2005.11.036 (2006). Article CAS PubMed Google Scholar ...