英文名称:Gamma-glutamylcysteine ligase (GCL) assay kit (micro assay 100T/96S) 英文同义词:Gamma-glutamylcysteine ligase (GCL) assay kit (micro assay 100T/96S) CAS号: 分子式: 分子量:0 EINECS号: 信息错误报告 您的Email: 按国家浏览Gamma-glutamylcysteine ligase (GCL) assay kit (micro assay 100...
Gromes R, Hothorn M, Lenherr ED, Rybin V, Scheffzek K, Rausch T. The redox switch of γ-glutamylcysteine ligase via a reversible monomer-dimer transition is a mechanism unique to plants. The Plant Journal. 2008; 54 :1063–1075.Gromes R, Hothorn M, Lenherr ED, Rybin V, Scheffzek K,...
-Glutamylcysteine synthetase (GCS; also referred to as glutamate-cysteine ligase, GLCL) catalyzes the rate-limiting reaction in glutathione (GSH) biosynthesis. The GCS holoenzyme is composed of a catalytic and regulatory subunit, each encoded by a unique gene. In addition to some conditions which ...
Under basal conditions, Keap1 functions as an ubiquitin ligase and targets Nrf2 for ubiquitination and proteasomal degradation, therefore leads to very low levels of free Nrf2. A number of stress situations, including oxidative stress and the presence of electrophiles, alter certain cysteine residues ...
Kinetic measurement by LC/MS of gamma-glutamylcysteine ligase activity(vol 827, pg 32, 2005) 来自 国家科技图书文献中心 喜欢 0 阅读量: 11 作者:K Chikh,F Flourie,K Arab,J Steghens 摘要: Correction:Kinetic measurement by LC/MS of gamma-glutamylcysteine ligase activity(vol 827, pg 32, 2005...
Glutamate-Cysteine LigaseEnzyme InhibitorsMolecular ConformationThe optical isomers of 3-amino-1-chloro-2-pentanone, which are the alpha-chloroketone analogs of L- and D-alpha-aminobutyrate, were synthesized and found to be highly potent irreversible inactivators of gamma-glutamylcysteine synthetase. ...
机译:beta-Naphthoflavone;Antioxidants;Gene Expression Regulation;Glutamate Cysteine Ligase genetics;β萘黄酮;抗氧化药;基因表达调控; 入库时间 2022-08-18 17:53:42 相似文献 外文文献 中文文献 专利 1. Overlapping antioxidant response element and PMA responseelement sequences mediate basal and beta-naph...
展开 关键词: Humans Glutamate-Cysteine Ligase Antioxidants Cloning, Molecular Base Sequence Regulatory Sequences, Nucleic Acid Transcription, Genetic Molecular Sequence Data Promoter Regions, Genetic DNA, Complementary DOI: 10.1006/bbrc.1995.1493 被引量: 440 年份...
The gene GLCLC encodes the catalytic subunit of gamma-glutamylcysteine synthetase (glutamate-cysteine ligase E.C. 6.3.2.2), the rate limiting enzyme for glutathione synthesis. When HepG2 cells were exposed to the serine/threonine phosphatase inhibitor okadaic acid (OA), increased expression of GLC...
Glutamate-Cysteine LigasePulmonary DiseaseChronic ObstructiveSmoking吸烟Glutathione (GSH) plays a major role in protecting the airways against oxidative stress. The rate-limiting enzyme in de novo GSH synthesis is gamma-glutamylcysteine synthetase (gamma-GCS), which is induced by acute exposure to GSH-...