The N-terminal and C-terminal halves of YpFabH share a high degree of symmetry, with the two halves arranging to form a thiolase fold motif charac- teristic of the FASII condensing enzymes19,20,48. The thiolase fold consists of two five stranded mixed β -sheets flanked either side by...
Also provided are methods for the biological production of P(3HB-co-3HV) copolymers in plants and bacteria utilizing propionyl-CoA produced through a variety of engineered metabolic pathways. Introduction into plants and bacteria of an appropriate β-ketothiolase, β-ketoacyl-CoA reductase, and ...
The 2.8 A crystal structure of peroxisomal 3-ketoacyl-CoA thiolase of Saccharomyces cerevisiae: a five-layered ababa-structure constructed from two core domains of identical topology. Structure 15, 797-808.Mathieu, M., Zeelen, J. P., Pauptit, R. A., Erdmann, R., ...
a mouse model of long-chain 3-ketoacyl-coa thiolase deficlency of mitochondrial fatty acid beta-oxidation is associated with low body mass, cold intoterance and hepatic steatosisdoi:10.1016/S0016-5085(08)80526-4Merriman, Raphael B.Qin, Wenning...