BETA-KETOACYL-COA SYNTHASE GENES, PROTEINS AND THEIR USESMALKIT AZACHIAVI SADKAADA ZAMIR
beta-Ketoacyl-acyl carrier protein (ACP) synthase III catalyzes the condensation of acetyl-CoA with malonyl-ACP in dissociated (Type II) fatty acid synthas... JT Tsay,W Oh,TJ Larson,... - 《Journal of Biological Chemistry》 被引量: 438发表: 1992年 Inhibition of fatty acid synthesis by...
Beta-Ketoacyl-acyl carrier protein (ACP) synthetase catalyzes the condensation reaction of fatty acid synthesis in Escherichia coli. The homogeneous enzyme reacts with hexanoyl-CoA to form hexanoyl-enzyme which was isolated and characterized. Hexanoyl-enzyme contains 2 mol of hexanoate/mol of enzyme ...
Examines contribution of FabG to coenzyme A (CoA) activity in Escherichia coli biosynthesis. Characterization of FabG as a 3-ketoacyl reductase of Pseudomo... Q Ren,Sierro,Nicolas - 《Journal of Bacteriology》 被引量: 91发表: 2000年 Nucleic acid sequences encoding β-ketoacyl-ACP synthase and...
Crystal structure of hexanoyl-CoA bound to β-ketoacyl reductase FabG4 of Mycobacterium tuberculosis Fab Gs, or beta-oxoacyl reductases, are involved in fatty acid synthesis. The reaction entails NADPH/NADH-mediated conversion of beta-oxoacyl-ACP (acyl-car... D Dutta,S Bhattacharyya,A Roychowdhur...
The present study provides evidence for a new rat liver microsomal enzyme, a short chain beta-ketoacyl (acetoacetyl)-CoA reductase, which is separate from the long chain beta-ketoacyl-CoA reductase component of the microsomal fatty acid ... MR Prasad,L Cook,R Vieth,... - 《Journal of ...
To further characterise the active site and substrate interactions of YpFabH, we attempted to co-crystallise YpFabH with acetyl-CoA. Unlike the apo-YpFabH structure, the active site cysteine (Cys112) of this complex is acetylated, with no CoA phosphopantetheine moiety visible within the ...
Acyl carrier protein (ACP)-dependent elongation of the n-C12 acyl primer mainly by one methylmalonyl-CoA unit was catalyzed by an E. coli fatty acid synthase preparation only in the presence of the expressed MAS domains. An ACP-dependent elongation of the n-C20 acyl primer by one ...
(CLF) activity; malonyl-CoA:ACP acyltransferase (MAT) activity; and 4′-phosphopantetheinyl transferase (PPTase) activity; (c) a nucleic acid sequence encoding an amino acid sequence that is at least about 65% identical, and more preferably at least about 75% identical, and more preferably at...
TriacylglycerolKey message Differences in FAE1 enzyme affinity for the acyl-CoA substrates, as well as the balance between the different pathways involved in their incorporation to triacylglycerol might be determinant of the different composition of the seed oil in Brassicaceae.Claver, Anade la Vega,...