beta.-Hydroxy-.alpha.-amino acids are obtained via serine hydroxymethyltransferase catalyzed condensation of aldehydes with glycine. The predominant product with most aldehydes is the L-erythro diastereomer. For example, succinic semialdehyde methyl ester is condensed with glycine in the process to ...
amino acids, peptidesβ-Hydroxy-a-amino acids are an important class of amino acids due to their inherent biological investigations[1] and as structural components of more complex biomolecules.[2] β-Hydroxy-a-amino acids have been used as intermediates in the asymmetric synthesis of other ...
SYNTHESES OF THE SYN AND ANTI ALPHA-AMINO-BETA-HYDROXY ACIDS OF VANCOMYCIN - (2S, 3R) AND (2R, 3R) P-CHLORO-3-HYDROXYTYROSINES Syntheses of (2S, 3R) and (2R, 3R) methyl p-chloro-3-hydroxytyrosinates 2 and 3 respectively, have been achieved from 3-chloro-4-hydroxybenzoic acid....
derivatives thereof β- hydroxy -α- two chiral template - tricyclo and with two chiral template synthesis of amino acid derivatives of β- hydroxy -α-;; imine within tricyclic imide fat and trans fat and then again in the preparation of such derivatives of β- hydroxy acids -α- Methods....
LOS (BETA) -HYDROXY- (ALPHA) -AMINO ACIDS ARE OBTAINED THROUGH A CATALYZED CONDITION OF HYDROXYMETHALITRANESE TRANSFER WITH GLYCINE. THE PREVAILING PRODUCT WITH THE MAJORITY OF ALDEHYDES IS L-ERITRO DIASTEREOMERO. FOR EXAMPLE: IN THE PROCESS, SUCCINIC SEMIALDEHYDE METHYL ESTER IS CONDENSED WITH ...
Makino,K,Goto,T,Hiroki,Y.,Hamada,Y."Stereoselective synthesis of anti-beta-hydroxy-alpha-amino acids through dynamic ki- netic resolution". Angew Chem.Int.Ed . 2004Kazuishi Makino,Takayuki Goto,Yasuhiro Hiroki,Yasumasa Hamada. Stereoselective Synthesis of anti-beta-Hydroxy-alpha-amino Acids ...
A general method for the synthesis of beta-alkyl alpha-hydroxy beta-amino and alpha- and gamma-alkyl substituted beta-hydroxy-gamma-amino acids is described. The synthesis of all three classes of amino acids proceeds through a common chiral alcohol intermediate that is ge...
EP0498680A1 1992年2月10日 1992年8月12日 Sankyo Company Limited New beta-amino-alpha-hydroxycarboxylic acids and their useEP0498680A1 * 1992年2月10日 1992年8月12日 Sankyo Company Limited New beta-amino-alpha-hydroxycarboxylic acids and their use...
Miller.Synthesis of β-hydroxy-α-amino acids by aldol condensation using a chiral phase transfer catalyst.Tetrahedron. 1991Gasparski C. M,Miller M. J.Synthesis of β-hydroxy-α-amino acids by aldol condensation using a chiral phase transfer catalyst.. Tetrahedron . 1991...
Isolation of beta-hydroxy alpha-aminoacid from copper complexes - by treating with hydrogen sulphide in aq. tert.-butanolIsolation of free beta-hydroxy-alpha-amino carboxylic acids (e.g. threonine or serine) from their Cu complexes is carried out by treating with H2S in an aq. medium contg....