Linoleic acid (LA) and beta-CD-NH2 molecule are covalently conjugated to form a beta-CD-LA molecule. The beta-CD-LA molecule can self-assemble into spherical micelles with an average particle size of about 50.75 +/- 13.58 nm, which is beneficial for blood circulation. The micelles has a ...
本发明中使用的术语“氨基酸”是指含有氨基(-nh2)和羧基(-cooh)官能团以及每 个氨基酸特有的侧链的有机化合物。氨基酸名称在本发明中也以标准的单字母或三字母代码表示,总结如下: [0076][0077][0078] 术语“多肽”、“肽”和“蛋白质”在本发明中互换使用以指代氨基酸残基的聚合物。这些术语还适用于其中一个或...
The CD58 binding site on human CD2 was recently shown by nuclear magnetic resonance structural data in conjunction with site-directed mutagenesis to be a highly charged surface area covering approximately 770A2 on the major AGFCC'C" face of the CD2 immunoglobulin-like (Ig-like) NH2-terminal dom...
The NH2-terminal aspartic acid was substituted with amino acids (Gly,... LSZL NDASDI,D Yamashiro,LI CHOH HAO,... - 《Chemical Biology & Drug Design》 被引量: 11发表: 2010年 THE SOLID‐PHASE SYNTHESIS OF α‐MELANOTROPIN HYDRAZIDE The solid-phase synthesis of -melanotropin hydrazide, a ...
Without per-6-NH2-b-CD, only a trace amount of 4a was seen, verifying that a catalyst was necessary for this reaction (Table 1, entry 1). We studied catalyst loads of 5, 10, 15 and 20mol% in our model reaction (entries 2-4), with the optimal amount being 15mol% (entry 4). ...
The invention relates to novel peptides of formula (I) Ac-Arg-X<1>-Asp-X<2>-X<3>-X<4>-X<5>-X<6>-NH2 which are biologically active as ligands of the integrin alpha v beta 6, wherein: Ac represents Acetyl, X<1> represents Ser, Gly, Thr, Asp, Arg, Val, Tyr, His or Ala...