陈昕教授通过“Molecular crosstalk between beta-catenin and Yap during cholangiocarcinoma development”专题,对肿瘤学基础研究的科研思路进行了探讨。陈昕教授及其团队主要从事肝癌生长过程中分子遗传学和信号通路研究,重点聚焦在Hippo/YAP/TAZ通...
As our in vitro analysis showed that Wnt/β-catenin/Esrrb signalling regulates the self-organisation and maintenance of naïve ES cells, we next asked whether this pathway plays a similar role in vivo, in the pre-implantation epiblast. To directly monitor Wnt signalling activity, we derived E4...
The Wnt-5a-derived hexapeptide Foxy-5 inhibits breast cancer metastasis in vivo by targeting cell motility. Clin Cancer Res. 2008;14:6556–63. Article PubMed Google Scholar Jorge E. Cortes SF, John Pagel, Chul Won Jung, Sung-Soo Yoon, Youngil Koh, Animesh Dev Pardanani, Robert S Haupt...
Description:Rabbit monoclonal (E247) antibody to Beta-Catenin. Specificity:Beta-Catenin (CTNB1); Catenin (Cadherin-associated Protein) beta 1. Applications:IHC, WB Reactivity:Human, Mouse Immunogen:Synthetic peptide corresponding to a N-terminal aa sequence of human ?-Catenin. ...
上海玉博生物科技有限公司 主要致力于“Rabbit monoclonal [E247] to beta Catenin Abcam ab32572 ”的生产销售。多年的“Rabbit monoclonal [E247] to beta Catenin Abcam ab32572 ”生产与销售的经验,与各行业新老用户建立了稳定的合作关系,我公司经营的产品名称深受
Flutamide alters β-catenin expression and distribution, and its interactions with E-cadherin in the porcine corpus luteum of mid- and late pregnancy. Flutamide alters beta-catenin expression and distribution, and its interactions with E-cadherin in the porcine corpus luteum of mid- and late ...
alsohaveaneffectontheadhesionmoleculesE.cadherin, Beta‘cateninand Cyclin D1.The Cyclin DI gene hadbeenshownto significantlyhigher after gene silencing ofBeta—catenin.RNAinterferenceBeta—cateninmadeUStounderstandbettertheroleof Beta’catenininWnt
5-Aza-2′-deoxycytidine References W.D. Foulkes, I.E. Smith, J.S. Reis-Filho, Triple-negative breast cancer. N. Engl. J. Med. 363, 1938–1948 (2010) Article PubMed CAS Google Scholar E.K. Millar, P.H. Graham, S.A. O’Toole, C.M. McNeil, L. Browne, A.L. Morey, S...
ZEB1. Consequences of a loss of E-cadherin are an impairment of cell-cell adhesion, which allows detachment of cells, and nuclear localization of beta-catenin. In addition to an accumulation of cancer stem cells, nuclear beta-catenin induces a gene expression pattern favoring tumor invasion, and...
(D,E) LLC1 cells were cultured and treated as in (A) and as monolayer culture. Cells were treated on day 4 and collected on day 6 (48 hr treatment), and expression of CSC related genes were assayed by qPCR. ANOVA(Dunnett) N = 3, *p ≤ 0.05 (D). Expression of PARP...