beta-transducin repeat-containing E3 ubiquitin protein ligase (beta-TrCP) serves as the substrate recognition subunit for the Skp1-Cullin1-F-box protein E3 ubiquitin ligase, which recognizes the double phosphorylated DSG (X)(2+n)S destruction motif in various substrates that are essential for ...
In the context of the present invention, a gene encoding a protein of interest is heterologous to the vector DNA in which it is inserted for cloning or expression, and it is heterologous to a host cell containing such a vector, in which it is expressed, e.g., a CHO cell. The terms ...
TBL1XR1, NT (TBL1XR1, IRA1, TBLR1, F-box-like/WD repeat-containing protein TBL1XR1, Nuclear receptor corepressor/HDAC3 complex subunit TBLR1, TBL1-related protein 1, Transducin beta-like 1X-related protein 1)供应商 MyBioSource产品...
化学名:TBL1XR1, NT (TBL1XR1, IRA1, TBLR1, F-box-like/WD repeat-containing protein TBL1XR1, Nuclear receptor corepressor/HDAC3 complex subunit TBLR1, TBL1-related protein 1, Transducin beta-like 1X-related protein 1) 英語化学名:TBL1XR1, NT (TBL1XR1, IRA1, TBLR1, F-box-like/...
Human protein beta TrcP (I; beta-transducin repeats containing protein), for directing proteins to the proteosome degradation pathways, has a 569 amino acid (aa) sequence (2), given in the specification. Independent claims are also included for the following: (1) peptide fragments (Ia) of (...
The present invention relates to compounds which bind to Beta Trans-ducin repeat-containing protein (PTrCP), and modulate the activity of 13TrCP. In particular, the invention relates to compounds which demonstrate optimised binding to PTrCP. The invention also relates to pharmaceutical compositions ...
In this study, I have identified an interaction between large T Antigen (TAg) and beta-transducin repeat containing protein 1 and 2 (βTrCP1/2), the substrate recognition factors of the Skp1-Cul1-F box (SCF ) ubiquitination complex. Immunofluorescence analyses revealed that TAg and βTrCP1,...
Beta-transducin repeat-containing protein 1 (β-TrCP1) is a substrate-recognition module of SCFβ-TrCP1 ubiquitin ligases and its subcellular distribution is known to be critical for target specificity. Heterogeneous nuclear ribonucleoprotein (hnRNP) U, an abundant nuclear protein, is known to be ...
Beta-transducin repeat-containing protein 1 (β-TrCP1) is a substrate-recognition module of SCF β-Tr CP 1 ubiquitin ligases and its subcellular distribution is known to be critical for target specificity. Heterogeneous nuclear ribonucleoprotein (hnRNP) U, an abundant nuclear protein, is known to...
Human protein beta TrcP (I; beta-transducin repeats containing protein), for directing proteins to the proteosome degradation pathways, has a 569 amino acid (aa) sequence (2), given in the specification. Independent claims are also included for the following: (1) peptide fragments (Ia) of (...