To examine whether alpha lipoic acid(LA)regulates high glucose-induced mesangial cell proliferation via mammalian target of rapamycin(mTOR)signaling. The cell proliferation and cycle were determined by methylthiazoletetrazolium(MTT)assay and flow cytometry, respectively. The mRNA expression of AMP-...
Alpha-lipoic acid (α-LA), a well-known antioxidant, was proved to active ALDH2 in nitrate tolerance and diabetic animal model. However, the therapeutic advantage of α-LA for heart failure and related signaling pathway have not been explored. This study was designed to examine the role of ...
答:Alpha lipoic acid (ALA or LA)是一种有效的治疗汞中毒的非处方药。不象DMSA和DMPS, LA可以作用到大脑,因此它可以把大脑中的汞转移出来或者是让汞更加深入。如果你的孩子刚刚汞中毒治疗不到三个月或者是体内的铜含量过高,都绝不可以使用LA, 因为LA会抑制铜的排泄。Alpha lipoic acid (ALA or LA)的中文名...
Here, we examined whether α-lipoic acid (α-LA), a natural antioxidant, attenuated retinal injury in diabetic mice. The α-LA was orally administered to control mice or mice with streptozotocin-induced diabetes. We found that α-LA reduced oxidative stress, decreased and increased retinal 4-...
Thesodium salt version of R-LAmay be better absorbed than free lipoic acid, likely because of it higher solubility. And is up to 12-times more effective than other alpha lipoic acid supplements.[xi]I use and highly recommend thePerformance Lab®Energystack. ...
The effects of two biothiols, homocysteine (Hcy), a risk factor for cardiovascular disease, and alpha-lipoic acid (alphaLA), a therapeutic antioxidant, on p44/42 mitogen-activated protein kinases (MAPK) phosphorylation were examined in NIH/3T3 fibroblasts. Cells grown in serum-containing media ...
Define Alpha-lipoic acid. Alpha-lipoic acid synonyms, Alpha-lipoic acid pronunciation, Alpha-lipoic acid translation, English dictionary definition of Alpha-lipoic acid. n. An organic acid, C8H14S2O2, that is essential for decarboxylation of pyruvate to
Alpha lipoic acid (ALA) induces the endogenous expression of DNAJB3 in C2C12 and HepG2 cells. (A) RT-PCR data showing the effect of 0.3 mM ALA for 24 h on the expression of representative components of the heat shock response in C2C12 cells. (B) Dose and time effects of ALA on the...
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α- Lipoic acid (LA) widely exists in various cells. Lipoic acid is a B-group vitamin, which has strong antioxidant and nerve nourishing effects. It has extremely high health care functions and medical value. It is called "universal antioxidant".It is mainly us...