A process for preparing a compound of formula (I), or salt thereon wherein X is CH2, O or a protected keto group, R is H, CH3, acetyl or a silyl protecting group comprises reacting a compound of formula (II) with a -chloroethyl chloroformate and hydrolysing the resulting intermediate. ...
PURPOSE:To reaction between a chloroformate and acetaldehyde is carried out in organic solvent in the presence of a tertiary amine to enable the high-yield production of the title compound of high purity, which is used as a starting compound of agricultural chemicals and medicines. CONSTITUTION:...
CONSTITUTION:The compound of formula II can be produced by reacting (A) 1mol of a chloroformate of formula I (R is cycloalkyl) with (B) preferably 0.5- 10.0mol, especially 2.0-4.0mol of acetaldehyde, in an organic solvent such as dichloromethane, carbon tetrachloride, acetonitrile, etc., ...
The invention also relates to the new carbonates described above and the method of producing them, which consists in reacting an alpha-halogenated chloroformate of formula: R2-CHX-O-COCl with an alcohol of formula R1OH in an inert solvent medium of the presence of an organic or inorganic ...
The amount of the tert-amine is 0.05-1.5mol, preferably 0.2-0.5mol per 1mol of the chloroformate.JINBO SUSUMUOTOMO KIKUOTOKUNAGA HIRONORIINAYOSHI YUKIHIKO